Moffitt / Mayo Clinic Physical Sciences in Oncology Center

"Our research investigates the evolutionary dynamics that drive cancers and uses our understanding of evolution against the cancer"



"Evolutionary and ecological dynamics of tumor-host interactions"


"Clinical translation of evolutionary and ecological principles"


"Bench-to-Bedside Core"




"Training and Outreach within the Moffitt PSOC"






PSOC Leadership

Robert A. Gatenby, M.D.

chair of Radiology


Robert J. Gillies, Ph.D.

chair of Cancer Imaging and Metabolism

Alexander R. A. Anderson, Ph.D.

chair of the IMO




Latest PSOC News



PSOC Spotlight: May 17th, 2017 Moffitt MRI Signals: Miles for Moffitt/Heiko Enderling, PhD





Educator Award: Congratulations to Dr. Heiko Enderling, Co-Lead for Moffitt PSOC's Education and Outreach core and chair of the PSON education working group, for being named 2016 Moffitt Research Educator of the Year.



FLiiCR Internship: Congratulations to our very own FLiiCR student Enakshi Sunassee on winning a student research award for her poster “Characterization of migration phenotype of pancreatic cancer cell lines” at last weekend’s Annual Biomedical Research Conference for Minority Students (ABRCMS), held at the Tampa Convention Center past week/weekend.

Recent Publications

Enriquez-Navas, P. M., Kam, Y., Das, T., Hassan, S., Silva, A., Foroutan, P., . . . Gatenby, R. A. (2016). Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer. Sci Transl Med, 8(327), 327ra324. doi: 10.1126/scitranslmed.aad7842

Gillies, R. J., Kinahan, P. E., & Hricak, H. (2016). Radiomics: Images Are More than Pictures, They Are Data. Radiology, 278(2), 563-577. doi: 10.1148/radiol.2015151169

Hawkins, S., Wang, H., Liu, Y., Garcia, A., Stringfield, O., Krewer, H., . . . Gillies, R. J. (2016). Predicting Malignant Nodules from Screening CT Scans. J Thorac Oncol, 11(12), 2120-2128. doi: 10.1016/j.jtho.2016.07.002

Rahme, R. J., Aoun, R. J., Pines, A. R., Swanson, K. R., & Bendok, B. R. (2016). Defining the Immune Phenotype for Glioblastoma Multiforme: One Step Closer to Understanding Our Enemy. World Neurosurg, 95, 576-577. doi: 10.1016/j.wneu.2016.08.063

Enriquez-Navas, P. M., Wojtkowiak, J. W., & Gatenby, R. A. (2015). Application of Evolutionary Principles to Cancer Therapy. Cancer Res, 75(22), 4675-4680. doi: 10.1158/0008-5472.CAN-15-1337

Hawkins-Daarud, A., Rockne, R., Corwin, D., Anderson, A. R., Kinahan, P., & Swanson, K. R. (2015). In silico analysis suggests differential response to bevacizumab and radiation combination therapy in newly diagnosed glioblastoma. J R Soc Interface, 12(109), 20150388. doi: 10.1098/rsif.2015.0388

Jackson, P. R., Juliano, J., Hawkins-Daarud, A., Rockne, R. C., & Swanson, K. R. (2015). Patient-specific mathematical neuro-oncology: using a simple proliferation and invasion tumor model to inform clinical practice. Bull Math Biol, 77(5), 846-856. doi: 10.1007/s11538-015-0067-7

Silva, A., Jacobson, T., Meads, M., Distler, A., & Shain, K. (2015). An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells. J Vis Exp(101), e53070. doi: 10.3791/53070

Khin, Z. P., Ribeiro, M. L., Jacobson, T., Hazlehurst, L., Perez, L., Baz, R., . . . Silva, A. S. (2014). A preclinical assay for chemosensitivity in multiple myeloma. Cancer Res, 74(1), 56-67. doi: 10.1158/0008-5472.CAN-13-2397


HIP IMO 2017:


The Moffitt HIP IMO is now under way! June 5th - July 28th. Follow @MoffittPSOC for updates.